Florida State University

Accepting new graduate students.

Dr. Mohamed Kabbaj

Professor of Biomedical Sciences & Neuroscience
Biomedical Sciences
MSR 3300H


•• Dr. Kabbaj is accepting a graduate students in collaboration with Dr. Z Wang. •• The focus of our research is to understand the neurobiology underlying individual differences and sex differences in depression and drug addiction. Another focus of our research is to examine epigenetic mechanisms underlying social behaviors.
Recent Publications
Akbarabadi A, Sadat-Shirazi MS, Kabbaj M, Nouri Zadeh-Tehrani S, Khalifeh S, Pirri F, Zarrindast MR (2021). Effects of Morphine and Maternal Care on Behaviors and Protein Expression of Male Offspring. Neuroscience, 466:58-76. PubMed
Bokros M, Sherwin D, Kabbaj MH, Wang Y (2021). Yeast Fin1-PP1 dephosphorylates an Ipl1 substrate, Ndc80, to remove Bub1-Bub3 checkpoint proteins from the kinetochore during anaphase. PLoS Genet, 17(5):e1009592. PubMed
Duclot F, Sailer L, Koutakis P, Wang Z, Kabbaj M (2020). Transcriptomic Regulations Underlying Pair-bond Formation and Maintenance in the Socially Monogamous Male and Female Prairie Vole. Biol Psychiatry, 0006-3223(20)32108-9. PubMed
Schoepfer KJ, Xu Y, Wilber AA, Wu W, Kabbaj M (2020). Sex differences and effects of the estrous stage on hippocampal-prefrontal theta communication. Physiol Rep, 8(22):e14646. PubMed
Strong CE, Hagarty DP, Brea Guerrero A, Schoepfer KJ, Cajuste SM, Kabbaj M (2020). Chemogenetic selective manipulation of nucleus accumbens medium spiny neurons bidirectionally controls alcohol intake in male and female rats. Sci Rep, 10(1):19178. PubMed
Strong CE, Kabbaj M (2020). Neural Mechanisms Underlying the Rewarding and Therapeutic Effects of Ketamine as a Treatment for Alcohol Use Disorder. Front Behav Neurosci, 14:593860. PubMed
Elvir L, Duclot F, Wang Z, Kabbaj M (2019). Epigenetic regulation of motivated behaviors by histone deacetylase inhibitors. Neurosci Biobehav Rev, 305-317. PubMed
Sailer L, Duclot F, Wang Z, Kabbaj M (2019). Consequences of prenatal exposure to valproic acid in the socially monogamous prairie voles. Sci Rep, 9(1):2453. PubMed
Schoepfer KJ, Strong CE, Saland SK, Wright KN, Kabbaj M (2019). Sex- and dose-dependent abuse liability of repeated subanesthetic ketamine in rats.. Physiol Behav, 60-69. PubMed
Strong CE, Wright KN, Kabbaj M (2019). Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density. eNeuro, 6(6). PubMed
Wright KN, Hagarty DP, Strong CE, Schoepfer KJ, Kabbaj M (2019). Sex-Dependent Ketamine Addiction-Like Behavior Profile Following Exposure to Chronic Mild Stress. Chronic Stress, . PubMed
Dossat AM, Wright KN, Strong CE, Kabbaj M (2018). Behavioral and biochemical sensitivity to low doses of ketamine: Influence of estrous cycle in C57BL/6 mice. Neuropharmacology, 30-41. PubMed
Higgins R, Kabbaj M, Hatcher A, Wang Y (2018). The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins. PLoS One, 13(1):e0191490. PubMed
Kabbaj M, Wang Z (2018). Neurobiology of motivated behaviors. Integr Zool, 13(6):613-615. PubMed
Saland SK, Kabbaj M (2018). Sex Differences in the Pharmacokinetics of Low-dose Ketamine in Plasma and Brain of Male and Female Rats. J Pharmacol Exp Ther, 367(3):393-404. PubMed
Strong CE, Kabbaj M (2018). On the safety of repeated ketamine infusions for the treatment of depression: Effects of sex and developmental periods. Neurobiol Stress, 166-175. PubMed
Wang W, Duclot F, Groveman BR, Carrier N, Qiao H, Fang XQ, Wang H, Xin W, Jiang XH, Salter MW, Ding XS, Kabbaj M, Yu XM (2018). Hippocampal protein kinase D1 is necessary for DHPG-induced learning and memory impairments in rats. PLoS One, 13(4):e0195095. PubMed
Wright KN, Dossat AM, Strong CE, Sailer LL, Pavlock SM, Kabbaj M (2018). Optogenetic inhibition of medial prefrontal cortex projections to the nucleus accumbens core and methyl supplementation via L-Methionine attenuates cocaine-primed reinstatement. Integr Zool, 13(6):795-803. PubMed
Wright KN, Kabbaj M (2018). Sex differences in sub-anesthetic ketamine's antidepressant effects and abuse liability. Curr Opin Behav Sci, 36-41. PubMed
Dossat AM, Jourdi H, Wright KN, Strong CE, Sarkar A, Kabbaj M (2017). Viral-mediated Zif268 expression in the prefrontal cortex protects against gonadectomy-induced working memory, long-term memory, and social interaction deficits in male rats. Neuroscience, 243-257. PubMed
Dossat AM, Sanchez-Gonzalez MA, Koutnik AP, Leitner S, Ruiz EL, Griffin B, Rosenberg JT, Grant SC, Fincham FD, Pinto JR, Kabbaj M (2017). Pathogenesis of depression- and anxiety-like behavior in an animal model of hypertrophic cardiomyopathy. FASEB J, 31(6):2492-2506. PubMed
Duclot F, Kabbaj M (2017). Comparative transcriptomic analysis of the effects of antidepressant drugs in stress-susceptible mice. Biol Psychiatry , 81(4):278-279. PubMed
Saland SK, Duclot F, Kabbaj M (2017). Integrative analysis of sex differences in the rapid antidepressant effects of ketamine in preclinical models for individualized clinical outcomes. Curr Opin Behav Sci, 19-26. PubMed
Strong CE, Schoepfer KJ, Dossat AM, Saland SK, Wright KN, Kabbaj M (2017). Locomotor sensitization to intermittent ketamine administration is associated with nucleus accumbens plasticity in male and female rats. Neuropharmacology, 195-203. PubMed
Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Wright KN, Mouzon E, Kabbaj M, Neve R, Turecki G, Shen L, Nestler EJ (2017). Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine. Neuroscience, 353:1-6. PubMed
Wright KN, Strong CE, Addonizio MN, Brownstein NC, Kabbaj M (2017). Reinforcing properties of an intermittent, low dose of ketamine in rats: effects of sex and cycle. Psychopharmacology (Berl), 234(3):393-401. PubMed
Duclot F, Perez-Taboada I, Wright KN, Kabbaj M (2016). Prediction of individual differences in fear response by novelty seeking, and disruption of contextual fear memory reconsolidation by ketamine. Neuropharmacology, 293-305. PubMed
Sarkar A, Kabbaj M (2016). Sex Differences in Effects of Ketamine on Behavior, Spine Density, and Synaptic Proteins in Socially Isolated Rats. Biol Psychiatry, 80(6):448-456. PubMed

All Publications PubMed

Lab Website

Neuro Grads and Postdocs

Michelle Crawford, Graduate Student

Florian Duclot, Affiliate - Biomedical sciences

Dollie Jennings, Graduate Student

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