Dr. Alan Spector
Distinguished Research Professor of Psychology & Neuroscience
- PDB B334
- Neural basis of gustation, animal psychophysics, sensory processes, regulation of ingestive behavior, taste preferences and aversions.
- Current Research
- Assessment of taste function in mice with genetic deletions of taste receptors • Analysis of alterations in taste function and ingestive behavior associated with gastric bypass surgery • Evaluation of taste function following targeted damage in central gustatory structures • Analysis of function following transection and regeneration of gustatory nerves.
- Recent Publications
Kalyanasundar B, Blonde GD, Spector AC, Travers SP, Electrophysiological responses to sugars and amino acids in the nucleus of the solitary tract of type 1 taste receptor double knockout mice, J Neurophysiol, 2020 PubMed Schier LA, Inui-Yamamoto C, Blonde GD, Spector AC, T1R2+T1R3-independent chemosensory inputs contributing to behavioral discrimination of sugars in mice, Am J Physiol Regul Integr Comp Physiol, 2019 PubMed Spector AC, Kapoor N, Price RK, Pepino MY, Livingstone MBE, Le Roux CW, Proceedings from the 2018 Association for Chemoreception Annual Meeting Symposium: Bariatric Surgery and Its Effects on Taste and Food Selection, Chem Senses, 2019 PubMed Schier LA, Hyde KM, Spector AC, Conditioned taste aversion versus avoidance: A re-examination of the separate processes hypothesis, PLoS One, 2019 PubMed Gero D, File B, Justiz J, Steinert RE, Frick L, Spector AC, Bueter M, Drinking microstructure in humans: A proof of concept study of a novel drinkometer in healthy adults, Appetite, 2019 PubMed Schier LA, Spector AC, The Functional and Neurobiological Properties of Bad Taste, Physiol Rev, 2019 PubMed Spector AC, Schier LA, Behavioral evidence that select carbohydrate stimuli activate T1R-independent receptor mechanisms, Appetite, 2018 PubMed Blonde GD, Travers SP, Spector AC, Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor, Am J Physiol Regul Integr Comp Physiol, 2018 PubMed Langhans W, Adan R, Arnold M, Banks WA, Card JP, Dailey MJ, Daniels D, de Kloet AD, de Lartigue G, Dickson S, Fedele S, Grill HJ, Jansson JO, Kaufman S, Kolar G, Krause E, Lee SJ, Le Foll C, Levin BE, Lutz TA, Mansouri A, Moran TH, Pacheco-López G, Ramachandran D, Raybould H, Rinaman L, Samson WK, Sanchez-Watts G, Seeley RJ, Skibicka KP, Small D, Spector AC, Tamashiro KL, Templeton B, Trapp S, Tso P, Watts AG, Weissfeld N, Williams D, Wolfrum C, Yosten G, Woods SC, New horizons for future research - Critical issues to consider for maximizing research excellence and impact, Mol Metab, 2018 PubMed Blonde GD, Spector AC, An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor, Chem Senses, 2017 PubMed Smith KR, Spector AC, Detection of maltodextrin and its discrimination from sucrose are independent of the T1R2 + T1R3 heterodimer, Am J Physiol Regul Integr Comp Physiol, 2017 PubMed Spector AC, le Roux CW, Munger SD, Travers SP, Sclafani A, Mennella JA, Proceedings of the 2015 ASPEN Research Workshop-Taste Signaling, JPEN J Parenter Enteral Nutr, 2017 PubMed Hyde KM, Blonde GD, le Roux CW, Spector AC, Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection, Physiol Behav, 2017 PubMed Schier LA, Blonde GD, Spector AC, Bilateral lesions in a specific subregion of posterior insular cortex impair conditioned taste aversion expression in rats, J Comp Neurol, 2016 PubMed Schier LA, Spector AC, Behavioral Evidence for More than One Taste Signaling Pathway for Sugars in Rats., J Neurosci, 2016 PubMed Mathes CM, Letourneau C, Blonde GD, le Roux CW, Spector AC, Roux-en-Y Gastric Bypass in Rats Progressively Decreases the Proportion of Fat Calories Selected from a Palatable Cafeteria Diet., Am J Physiol Regul Integr Comp Physiol, 2016 PubMed Blonde GD, Bales MB, Spector AC, Extensive lesions in rat insular cortex significantly disrupt taste sensitivity to NaCl and KCl and slow salt discrimination learning, PLoS One, 2015 PubMed Spector AC, Blonde GD, Henderson RP, Treesukosol Y, Hendrick P, Newsome R, Fletcher FH, Tang T, Donaldson JA, A new gustometer for taste testing in rodents, Chem Senses, 2015 PubMed Mathes CM, Bohnenkamp RA, Blonde GD, Letourneau C, Corteville C, Bueter M, Lutz TA, le Roux CW, Spector AC, Gastric bypass in rats does not decrease appetitive behavior towards sweet or fatty fluids despite blunting preferential intake of sugar and fat, Physiol Behav, 2015 PubMed Spector AC, Behavioral analyses of taste function and ingestion in rodent models., Physiol Behav, 2015 PubMed