Florida State University

Dr. Alan Spector

Distinguished Research Professor of Psychology & Neuroscience

PDB B334


Neural basis of gustation, animal psychophysics, sensory processes, regulation of ingestive behavior, taste preferences and aversions.
Current Research
Assessment of taste function in mice with genetic deletions of taste receptors • Analysis of alterations in taste function and ingestive behavior associated with gastric bypass surgery • Evaluation of taste function following targeted damage in central gustatory structures • Analysis of function following transection and regeneration of gustatory nerves.
Recent Publications
Kalyanasundar B, Blonde GD, Spector AC, Travers SP (2020). Electrophysiological responses to sugars and amino acids in the nucleus of the solitary tract of type 1 taste receptor double knockout mice. J Neurophysiol, 123(2):843-859. PubMed
Gero D, File B, Justiz J, Steinert RE, Frick L, Spector AC, Bueter M (2019). Drinking microstructure in humans: A proof of concept study of a novel drinkometer in healthy adults. Appetite, 47-60. PubMed
Schier LA, Hyde KM, Spector AC (2019). Conditioned taste aversion versus avoidance: A re-examination of the separate processes hypothesis. PLoS One, 14(6):e0217458. PubMed
Schier LA, Inui-Yamamoto C, Blonde GD, Spector AC (2019). T1R2+T1R3-independent chemosensory inputs contributing to behavioral discrimination of sugars in mice. Am J Physiol Regul Integr Comp Physiol, 316(5):R448-R462. PubMed
Schier LA, Spector AC (2019). The Functional and Neurobiological Properties of Bad Taste. Physiol Rev, 99(1):605-663. PubMed
Spector AC, Kapoor N, Price RK, Pepino MY, Livingstone MBE, Le Roux CW (2019). Proceedings from the 2018 Association for Chemoreception Annual Meeting Symposium: Bariatric Surgery and Its Effects on Taste and Food Selection. Chem Senses, 44(3):155-163. PubMed
Blonde GD, Travers SP, Spector AC (2018). Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor. Am J Physiol Regul Integr Comp Physiol, 314(6):R802-R810. PubMed
Spector AC, Schier LA (2018). Behavioral evidence that select carbohydrate stimuli activate T1R-independent receptor mechanisms. Appetite, 26-31. PubMed
Blonde GD, Spector AC (2017). An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor. Chem Senses, 42(5):393-404. PubMed
Hyde KM, Blonde GD, le Roux CW, Spector AC (2017). Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection. Physiol Behav, 4-12. PubMed
Smith KR, Spector AC (2017). Detection of maltodextrin and its discrimination from sucrose are independent of the T1R2 + T1R3 heterodimer. Am J Physiol Regul Integr Comp Physiol, 313(4):R450-R462. PubMed
Spector AC, le Roux CW, Munger SD, Travers SP, Sclafani A, Mennella JA (2017). Proceedings of the 2015 ASPEN Research Workshop-Taste Signaling. JPEN J Parenter Enteral Nutr, 41(1):113-124. PubMed
Mathes CM, Letourneau C, Blonde GD, le Roux CW, Spector AC (2016). Roux-en-Y Gastric Bypass in Rats Progressively Decreases the Proportion of Fat Calories Selected from a Palatable Cafeteria Diet.. Am J Physiol Regul Integr Comp Physiol, 310(10):R952-9. PubMed
Schier LA, Blonde GD, Spector AC (2016). Bilateral lesions in a specific subregion of posterior insular cortex impair conditioned taste aversion expression in rats. J Comp Neurol, 524(1):54-73. PubMed
Schier LA, Spector AC (2016). Behavioral Evidence for More than One Taste Signaling Pathway for Sugars in Rats.. J Neurosci, 36(1):113-24. PubMed
Blonde GD, Bales MB, Spector AC (2015). Extensive lesions in rat insular cortex significantly disrupt taste sensitivity to NaCl and KCl and slow salt discrimination learning. PLoS One, 10(2):e0117515. PubMed
Mathes CM, Bohnenkamp RA, Blonde GD, Letourneau C, Corteville C, Bueter M, Lutz TA, le Roux CW, Spector AC (2015). Gastric bypass in rats does not decrease appetitive behavior towards sweet or fatty fluids despite blunting preferential intake of sugar and fat. Physiol Behav, 179-88. PubMed
Spector AC (2015). Behavioral analyses of taste function and ingestion in rodent models.. Physiol Behav, 152(Pt B):516-26. PubMed
Spector AC, Blonde GD, Henderson RP, Treesukosol Y, Hendrick P, Newsome R, Fletcher FH, Tang T, Donaldson JA (2015). A new gustometer for taste testing in rodents. Chem Senses, 40(3):187-96. PubMed

All Publications PubMed

Training Grant Opportunities

Neuro Grads and Postdocs

Ginger Blonde, Graduate Student

Elizabeth Hamel, Graduate Student

Valentina Nisi, Lab Tech

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