Florida State University

Dr. Alan Spector

Distinguished Research Professor of Psychology & Neuroscience

Faculty
Psychology
PDB B334
645-7883

spector@neuro.fsu.edu

Interest
Neural basis of gustation, animal psychophysics, sensory processes, regulation of ingestive behavior, taste preferences and aversions.
Current Research
Assessment of taste function in mice with genetic deletions of taste receptors • Analysis of alterations in taste function and ingestive behavior associated with gastric bypass surgery • Evaluation of taste function following targeted damage in central gustatory structures • Analysis of function following transection and regeneration of gustatory nerves.
Recent Publications
Gero D, File B, Alceste D, Frick LD, Serra M, Ismaeil AE, Steinert RE, Spector AC, Bueter M (2021). Microstructural changes in human ingestive behavior after Roux-en-Y gastric bypass during liquid meals. JCI Insight, 6(15):e136842. PubMed
Redpath TL, Livingstone MBE, Dunne AA, Boyd A, le Roux CW, Spector AC, Price RK (2021). Methodological issues in assessing change in dietary intake and appetite following gastric bypass surgery: A systematic review. Obes Rev, 22(6):e13202. PubMed
Bales MB, Spector AC (2020). Chemospecific deficits in taste sensitivity following bilateral or right hemispheric gustatory cortex lesions in rats. J Comp Neurol, 528(16):2729-2747. PubMed
Blonde GD, Spector AC (2020). Masking the Detection of Taste Stimuli in Rats: NaCl and Sucrose. . Chem Senses, 45(5):359-370. PubMed
Inui-Yamamoto C, Blonde GD, Schmid F, Mariotti L, Campora M, Inui T, Schier LA, Spector AC (2020). Neural Isolation of the Olfactory Bulbs Severely Impairs Taste-Guided Behavior to Normally Preferred, But Not Avoided, Stimuli. eNeuro, 7(2):ENEURO.0026-20. PubMed
Jiang E, Blonde GD, Garcea M, Spector AC (2020). ENaC-Dependent Sodium Chloride Taste Responses in the Regenerated Rat Chorda Tympani Nerve After Lingual Gustatory Deafferentation Depend on the Taste Bud Field Reinnervated. Chem Senses, 45(4):249-259. PubMed
Kalyanasundar B, Blonde GD, Spector AC, Travers SP (2020). Electrophysiological responses to sugars and amino acids in the nucleus of the solitary tract of type 1 taste receptor double knockout mice. J Neurophysiol, 123(2):843-859. PubMed
Qualls-Creekmore E, Marlatt KL, Aarts E, Bruce-Keller A, Church TS, Clément K, Fisher JO, Gordon-Larsen P, Morrison CD, Raybould HE, Ryan DH, Schauer PR, Spector AC, Spetter MS, Stuber GD, Berthoud HR, Ravussin E (2020). What Should I Eat and Why? The Environmental, Genetic, and Behavioral Determinants of Food Choice: Summary from a Pennington Scientific Symposium. Obesity , 28(8):1386-1396. PubMed
Gero D, File B, Justiz J, Steinert RE, Frick L, Spector AC, Bueter M (2019). Drinking microstructure in humans: A proof of concept study of a novel drinkometer in healthy adults. Appetite, 47-60. PubMed
Schier LA, Hyde KM, Spector AC (2019). Conditioned taste aversion versus avoidance: A re-examination of the separate processes hypothesis. PLoS One, 14(6):e0217458. PubMed
Schier LA, Inui-Yamamoto C, Blonde GD, Spector AC (2019). T1R2+T1R3-independent chemosensory inputs contributing to behavioral discrimination of sugars in mice. Am J Physiol Regul Integr Comp Physiol, 316(5):R448-R462. PubMed
Schier LA, Spector AC (2019). The Functional and Neurobiological Properties of Bad Taste. Physiol Rev, 99(1):605-663. PubMed
Spector AC, Kapoor N, Price RK, Pepino MY, Livingstone MBE, Le Roux CW (2019). Proceedings from the 2018 Association for Chemoreception Annual Meeting Symposium: Bariatric Surgery and Its Effects on Taste and Food Selection. Chem Senses, 44(3):155-163. PubMed
Blonde GD, Travers SP, Spector AC (2018). Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor. Am J Physiol Regul Integr Comp Physiol, 314(6):R802-R810. PubMed
Spector AC, Schier LA (2018). Behavioral evidence that select carbohydrate stimuli activate T1R-independent receptor mechanisms. Appetite, 26-31. PubMed
Blonde GD, Spector AC (2017). An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor. Chem Senses, 42(5):393-404. PubMed
Hyde KM, Blonde GD, le Roux CW, Spector AC (2017). Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection. Physiol Behav, 4-12. PubMed
Smith KR, Spector AC (2017). Detection of maltodextrin and its discrimination from sucrose are independent of the T1R2 + T1R3 heterodimer. Am J Physiol Regul Integr Comp Physiol, 313(4):R450-R462. PubMed
Spector AC, le Roux CW, Munger SD, Travers SP, Sclafani A, Mennella JA (2017). Proceedings of the 2015 ASPEN Research Workshop-Taste Signaling. JPEN J Parenter Enteral Nutr, 41(1):113-124. PubMed
Mathes CM, Letourneau C, Blonde GD, le Roux CW, Spector AC (2016). Roux-en-Y Gastric Bypass in Rats Progressively Decreases the Proportion of Fat Calories Selected from a Palatable Cafeteria Diet.. Am J Physiol Regul Integr Comp Physiol, 310(10):R952-9. PubMed
Schier LA, Spector AC (2016). Post-oral sugar detection rapidly and chemospecifically modulates taste-guided behavior. Am J Physiol Regul Integr Comp Physiol, 311(4):R742-R755. PubMed

All Publications PubMed

Training Grant Opportunities

Neuro Grads and Postdocs

Ginger Blonde, Affiliate - Psychology

Carolina Cawthon, Postdoctoral Associate

Elizabeth Hamel, Graduate Student

Valentina Nisi, Lab Tech

Valentina Nisi, Graduate Student

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