Dr. Derek Nee
Assistant Professor of Psychology & Neuroscience
- PDB B433
- Our lab examines how behavior is guided by internal representations to perform goal-directed action. This requires understanding cognitive control, which promotes goal-relevant processing over habitual tendencies, and working memory, which sustains and transforms information that is no longer available to the senses. We study humans using functional MRI (fMRI), transcranial magnetic stimulation (TMS), experimental psychology, and combinations thereof.
- Current Research
- In the domain of cognitive control, our current focus is on detailing the dynamic interactions among areas of the prefrontal cortex and sub-cortex that support goal-directed cognition. Using fMRI, we construct models of directed regional influences during situations requiring cognitive control. These models are then tested using TMS to observe predicted consequences of neural perturbation on brain networks and behavior. In the domain of working memory, we are presently examining the neural mechanisms underlying prioritizing information in mind (e.g. focusing on one thing vs. holding something thing in mind for later). This involves fitting models of neural representation to multi-variate fMRI data. We are also interested in how the medial temporal lobe and prefrontal cortex promote binding of short-term information to support the construction of novel associations for higher-level cognition.
- Recent Publications
Nee DE , fMRI replicability depends upon sufficient individual-level data, Commun Biol, 2019 PubMed Eich TS, Gonçalves BMM, Nee DE, Razlighi Q, Jonides J, Stern Y, Inhibitory Selection Mechanisms in Clinically Healthy Older and Younger Adults, J Gerontol B Psychol Sci Soc Sci, 2018 PubMed Nee DE, D'Esposito M, The Representational Basis of Working Memory, Curr Top Behav Neurosci, 2018 PubMed Badre D, Nee DE, Frontal Cortex and the Hierarchical Control of Behavior, Trends Cogn Sci, 2018 PubMed Lorenc ES, Sreenivasan KK, Nee DE, Vandenbroucke ARE, D'Esposito M, Flexible Coding of Visual Working Memory Representations during Distraction, J Neurosci, 2018 PubMed Tambini A, Nee DE, D'Esposito M, Hippocampal-targeted Theta-burst Stimulation Enhances Associative Memory Formation, J Cogn Neurosci, 2018 PubMed Oberauer K, Lewandowsky S, Awh E, Brown GDA, Conway A, Cowan N, Donkin C, Farrell S, Hitch GJ, Hurlstone MJ, Ma WJ, Morey CC, Nee DE, Schweppe J, Vergauwe E, Ward G, Benchmarks for models of short-term and working memory, Psychol Bull, 2018 PubMed Oberauer K, Lewandowsky S, Awh E, Brown GDA, Conway A, Cowan N, Donkin C, Farrell S, Hitch GJ, Hurlstone MJ, Ma WJ, Morey CC, Nee DE, Schweppe J, Vergauwe E, Ward G, Benchmarks provide common ground for model development: Reply to Logie (2018) and Vandierendonck (2018), Psychol Bull, 2018 PubMed Cyr M, Nee DE, Nelson E, Senger T, Jonides J, Malapani C, Effects of proactive interference on non-verbal working memory, Cogn Process, 2017 PubMed Nee DE, D'Esposito M, Causal evidence for lateral prefrontal cortex dynamics supporting cognitive control, Elife, 2017 PubMed Nee DE, D'Esposito M, The hierarchical organization of the lateral prefrontal cortex, Elife, 2016 PubMed Rahnev D, Nee DE, Riddle J, Larson AS, D'Esposito M, Causal evidence for frontal cortex organization for perceptual decision making, Proc Natl Acad Sci U S A, 2016 PubMed Jahn A, Nee DE, Alexander WH, Brown JW, Distinct Regions within Medial Prefrontal Cortex Process Pain and Cognition, J Neurosci, 2016 PubMed