Dr. Elizabeth Hammock
Assistant Professor of Psychology & Neuroscience
- PDB B221
- We use genetic, molecular, cellular, and behavioral techniques to understand the neurobiological mechanisms of social and affective behaviors in developing and mature mammals. Some Big Questions in our lab: How are social brains built? How does nurturing care-giving impact the developing brain? How does social-emotional neglect affect brain development? What are the mechanics of gene x environment interactions? Currently, our work focuses on oxytocin and vasopressin in rodent models of experience-dependent developmental plasticity. Our goal is to contribute to the understanding of molecular and cellular mechanisms underlying the interaction between life experience and genetic variation. Such knowledge should facilitate the development of more effective intervention strategies used to promote better outcomes in individuals with atypical development and adverse early experiences.
- Current Research
- Do developmentally transient neocortical oxytocin receptors shape experience-dependent development? What is/are the role(s) of oxytocin receptors in the neonatal oronasal cavity? What do neocortical vasopressin 1a receptors do in the neonatal brain? Are there peripheral biomarkers of mental illness/health in development? How does sensitive period social neglect shape neocortical development? Design and 3D printing of custom research tools.
- Recent Publications
Vaidyanathan R, Hammock EA, Oxytocin receptor dynamics in the brain across development and species, Dev Neurobiol., 2017 PubMed Greenwood MA, Hammock EA, Oxytocin receptor binding sites in the periphery of the neonatal mouse, PLoS One. , 2017 PubMed Hammock EA, Developmental Perspectives on Oxytocin and Vasopressin, Neuropsychopharmacology, 2015 PubMed Roth TL, Raineki C, Salstein L, Perry R, Sullivan-Wilson TA, Sloan A, Lalji B, Hammock EA, Wilson DA, Levitt P, Okutani F, Kaba H, Sullivan RM, Neurobiology of secure infant attachment and attachment despite adversity: a mouse model, Genes Brain Behav, 2013 PubMed Hammock EA, Law CS, Levitt P, Vasopressin eliminates the expression of familiar odor bias in neonatal female mice through V1aR, Horm Behav, 2013 PubMed Hammock EA, Levitt P, Oxytocin receptor ligand binding in embryonic tissue and postnatal brain development of the C57BL/6J mouse, Front Behav Neurosci, 2013 PubMed Hammock EA, Veenstra-VanderWeele J, Yan Z, Kerr TM, Morris M, Anderson GM, Carter CS, Cook EH, Jacob S, Examining autism spectrum disorders by biomarkers: example from the oxytocin and serotonin systems, J Am Acad Child Adolesc Psychiatry, 2012 PubMed Hammock EA, Levitt P, Modulation of parvalbumin interneuron number by developmentally transient neocortical vasopressin receptor 1a (V1aR), Neuroscience, 2012 PubMed Hammock EA, Levitt P, Developmental Expression Mapping of a Gene Implicated in Multiple Neurodevelopmental Disorders, A2bp1 (Fox1), Dev Neurosci, 2011 PubMed Hammock EA, Eagleson KL, Barlow S, Earls LR, Miller DM 3rd, Levitt P, Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain, Neural Dev, 2010 PubMed Hammock EA, Young LJ, Microsatellite instability generates diversity in brain and sociobehavioral traits, Science, 2005 PubMed